Synthesis and Characterization of Doped Bioactive Glasses

Ahmed Bachar (1) , Rémy Catteaux (2, 3) , Cédric Duée (4) , Françoise Désanglois (3) , Isabelle Lebecq (3) , Cyrille Albert-Mercier (3) , Claudine Follet-Houttemane (3, 5)

1 CEMHTI - Conditions Extrêmes et Matériaux : Haute Température et Irradiation
2 CEED - Centre for Earth Evolution and Dynamics [Oslo]
3 LMCPA - Laboratoire des Matériaux Céramiques et Procédés Associés - EA 2443
4 BRGM - Bureau de Recherches Géologiques et Minières (BRGM)
5 INSA Hauts-De-France - INSA Institut National des Sciences Appliquées Hauts-de-France

Bioactive glasses have been studied for several years. Hench has been the first to show their interest as bone substitutes. Bioglass 45S5 is the best known. This work reviews bioactive glasses of the SiO2, CaO, and Na2O domain. P, F, and N dopings are also presented. Mixture designs have been used to synthesize the best bioactive glass and to limit the essays. Structures have been studied by NMR analyses. Mechanic properties have been studied as a function of N ratios. Bioactivity has been determined by Fourier Transform Infrared (FTIR) spectroscopy in terms of time of HCA layer’s nucleation. The layer’s thickness has been estimated by Scanning Electron Microscopy coupled with Energy Dispersion Spectroscopy (SEM-EDS) analyses. The last part is about sol-gel synthesis and the Ag doping of an invert glass with 47% SiO2, 26.5% CaO, 21.5% Na2O, and 5% P2O5 composition.

Mots clés: Melt-quench synthesis; Sol-gel; Mixture designs; Doping; Mechanic properties

Domaines: Planète et Univers [physics]; Chimie; Sciences de la Terre; Sciences du Vivant [q-bio]; Sciences de l'ingénieur [physics]

Ahmed Bachar, Rémy Catteaux, Cédric Duée, Françoise Désanglois, Isabelle Lebecq, et al.. Synthesis and Characterization of Doped Bioactive Glasses. Gurbinder Kaur. Biomedical, Therapeutic and Clinical Applications of Bioactive Glasses, Elsevier, pp.69-123, 2019, 9780081021965. ⟨10.1016/B978-0-08-102196-5.00003-3⟩. ⟨hal-02915319⟩